What do you do when your friend is turning into Gregory House M.D.?

If he could save lives, then i think it's better if he stayed that way. But there are people who are like that. It's just whether you're a good enough of a friend (yeah Wilson and all the other doctors seem to be good friends of House) then it's alright. Dr. House understands his problems, it's just that he knows he was made that way and he accepts it. And he goes around knowing he acts like an *** to his good friends.